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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIPK1
All Species:
23.33
Human Site:
Y549
Identified Species:
73.33
UniProt:
Q86Z02
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z02
NP_689909.2
1210
130843
Y549
C
K
R
R
V
H
M
Y
D
T
V
S
Q
I
K
Chimpanzee
Pan troglodytes
XP_001151260
1210
130923
Y549
C
K
R
R
V
H
M
Y
D
T
V
S
Q
I
K
Rhesus Macaque
Macaca mulatta
XP_001111238
1210
130747
Y549
C
K
R
R
V
H
M
Y
D
T
V
S
Q
I
K
Dog
Lupus familis
XP_533012
1209
130666
Y549
C
K
R
R
V
H
M
Y
D
T
V
S
Q
I
K
Cat
Felis silvestris
Mouse
Mus musculus
O88904
1210
130704
Y549
C
K
R
R
V
H
M
Y
D
T
V
S
Q
I
K
Rat
Rattus norvegicus
A4L9P5
1211
130782
Y549
C
K
R
R
V
H
M
Y
D
T
V
S
Q
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q2TAE3
750
84138
Y104
K
H
I
N
E
V
Y
Y
A
K
K
K
R
R
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49657
908
95884
G261
L
R
N
T
N
F
R
G
V
S
L
N
L
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98.3
N.A.
97.6
97.2
N.A.
N.A.
N.A.
22.8
N.A.
N.A.
22.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
99.5
99
N.A.
98.8
98.4
N.A.
N.A.
N.A.
35.5
N.A.
N.A.
36.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% A
% Cys:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% G
% His:
0
13
0
0
0
75
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
0
13
0
0
0
0
0
0
0
0
0
0
75
0
% I
% Lys:
13
75
0
0
0
0
0
0
0
13
13
13
0
0
75
% K
% Leu:
13
0
0
0
0
0
0
0
0
0
13
0
13
0
0
% L
% Met:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
13
13
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% Q
% Arg:
0
13
75
75
0
0
13
0
0
0
0
0
13
13
13
% R
% Ser:
0
0
0
0
0
0
0
0
0
13
0
75
0
0
0
% S
% Thr:
0
0
0
13
0
0
0
0
0
75
0
0
0
13
0
% T
% Val:
0
0
0
0
75
13
0
0
13
0
75
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
88
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _